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Field-based 3D-QSAR studies on amide- and urea-containing NAMPT inhibitors

Fikriye Ozgencil, Gokcen Eren 

Chemometrics and Intelligent Laboratory Systems

242: 104984 (2023)

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The potential of 4-aryl-6-morpholino-3(2H)-pyridazinone-2- arylpiperazinylacetamide as a new scaffold for SIRT2 inhibition: in silico approach guided by pharmacophore mapping and molecular docking

Murat Kadir Sukuroglu, Mahmut Gozelle,

Yesim Ozkan, Gokcen Eren

Medicinal Chemistry Research

30: 1915 (2021)

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Hit evaluation results in 5-benzyl-1,3,4-thiadiazole-2-carboxamide based SIRT2-selective inhibitor with improved affinity and selectivity

Mahmut Gozelle, Selen Gozde Kaya, Ahmet Bugra Aksel, Erva Ozkan, Filiz Bakar-Ates, Yesim Ozkan, Gokcen Eren 

Bioorganic Chemistry

123: 105746 (2022)


Hit-to-lead optimization on aryloxybenzamide derivative virtual screening hit against SIRT

Semih Yagci, Mahmut Gozelle, Selen Gozde Kaya, Yesim Ozkan, Ahmet Bugra Aksel, Filiz Bakar-Ates, Yasemin Dundar, Gokcen Eren

Bioorganic & Medicinal Chemistry

30: 115961 (2021)


Identification of small-molecule urea derivatives as novel NAMPT inhibitors via pharmacophore-based virtual screening

Fikriye Ozgencil, Gokcen Eren, Yesim Ozkan, Sezen Guntekin-Ergunc, Rengul Cetin-Atalay

Bioorganic & Medicinal Chemistry

20: 115217 (2020)


Homology Modeling of Human Nicotinamide/Nicotinic Acid Mononucleotide Adenylyltransferase 2: Insights into Isoenzyme-Specific Differences Using Molecular Docking Simulations

Gokcen Eren

Letters in Drug Design & Discovery

14: 727 (2017)


Pharmacophore modeling and virtual screening studies to identify novel selective SIRT2 inhibitors

Gokcen Eren, Agostino Bruno, Sezen Guntekin-Ergun, Rengul Cetin-Atalay, Fikriye Ozgencil, Yesim Ozkan, Mahmut Gozelle, Selen Gozde Kaya,
Gabriele Costantino

Journal of Molecular Graphics and Modelling

89: 60e73 (2019)

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